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Why we recommend Rejuran every 2 weeks for the first 3 sessions, then consistently once a month?

Why we recommend Rejuran every 2 weeks for the first 3 sessions, then consistently once a month? Beomgye, Pyeongchon, Beomgye Station, Pyeongchon Station, Hogye-dong, Bisan-dong, Gwanyang-dong, Dongan-gu, Indeogwon, Geumjeong, Anyang

7/6/2026

This is a procedure note for Why we recommend Rejuran every 2 weeks for the first 3 sessions, then consistently once a month? at Beomgye(Opening Soon) KKEUT Korean Clinic.

What people searching for Rejuran cycles are most curious about first is, why the initial focus is on 3 sessions at 2-week intervals, and then transitions to 1-month intervals.



PN (polynucleotide), the main ingredient of Rejuran, works by helping to repair damaged dermal cells' DNA and promoting collagen synthesis.



It's not an ingredient that hydrates or smooths the skin's surface, but rather a concept of directly supplying the dermis with materials for skin regeneration.







Initial Intensive Period — The Principle of 3 Sessions in 2 Weeks



When the PN ingredient is injected into the dermal layer, cell regeneration reactions are activated.



The duration for which this reaction is maintained is approximately 2 weeks.



If the next session is performed before 2 weeks pass, new stimulation is added before the regenerative environment completely diminishes, creating a cumulative effect where collagen synthesis reactions overlap.







After the age of 30, the skin's natural cell regeneration rate slows down.



When skin regeneration is diminished, the regenerative response is not sufficiently activated by a single treatment's stimulation alone.



The initial intensive treatments at 2-week intervals serve to forcefully activate the slowed regeneration cycle, and only after completing 3 sessions does the regenerative foundation in the dermal layer truly become established.







Maintenance Period — Reasons for Transitioning to 1-Month Intervals



After the initial 3 sessions, it transitions to a phase of maintaining and building upon the already activated regenerative response.



A 1-month interval aligns with the collagen production cycle, and consistently maintaining this cycle gradually increases collagen density in the dermal layer and builds skin elasticity.



If the maintenance period is discontinued after completing the initial 3 sessions, the collagen synthesis reaction gradually returns to baseline levels.



A point of caution during the Rejuran cycle maintenance phase is when patients arbitrarily extend or stop intervals once they start to feel the effects.



Since the collagen synthesis reaction gradually diminishes without continuous stimulation, consistently maintaining a 1-month interval is key.







The Rejuran cycle is adjusted according to skin condition and age.



If photoaging has progressed or skin regeneration is low, the initial intensive period may be extended to 4 sessions, or the maintenance interval adjusted to 6-8 weeks.



For those in their 20s or 30s with good skin condition, distinct changes are often felt even with just the initial 3 intensive sessions, and the maintenance interval may be set to 6 weeks.



PN-based skin boosters have recently seen their patents expire, leading to the rapid launch of new products under various names.



More important than which brand you receive the treatment with is that how consistently you adhere to the Rejuran cycle determines the final outcome.







Kkeut Oriental Medicine Clinic's Unique Rejuran Differentiation



At Kkeut Oriental Medicine Clinic, during Rejuran procedures, the embossing phenomenon is always checked.



Embossing is the phenomenon where the skin surface rises convexly when the PN ingredient is accurately injected into the dermal layer; this phenomenon must be confirmed to verify that the medication has properly entered the dermal layer.



Kkeut Oriental Medicine Clinic allows you to directly confirm the embossing phenomenon in the mirror after the procedure.







Kkeut Oriental Medicine Clinic selects the treatment method most suitable for the patient's skin condition and goals from manual injection, Potenza pumping tip, or Dermashine (injector).



Instead of sticking to one method, Kkeut Oriental Medicine Clinic's approach is to apply the most effective technique by considering skin sensitivity and absorption rate.







As consistency is key for Rejuran, Kkeut Oriental Medicine Clinic is lowering the cost burden to create an environment where continuous treatment is realistically possible.







Frequently Asked Questions


Q. Can I receive Rejuran treatments at intervals shorter than 2 weeks?


A. If the Rejuran cycle is set shorter than 2 weeks, additional stimulation would be applied before the regenerative response from the previous treatment has fully settled. This can lead to insufficient skin recovery capacity, so it is generally not recommended, and Kkeut Oriental Medicine Clinic adjusts intervals after checking the skin condition.


Q. Can I skip the initial 3 intensive Rejuran sessions and go straight to 1-month intervals?


A. If the initial intensive phase of the Rejuran cycle is omitted, you would transition to the maintenance phase without a sufficiently established dermal regeneration foundation. The cumulative effect is likely to be lower, so we recommend transitioning after completing 3 intensive sessions.


Q. If I consistently follow the Rejuran cycle, when can I expect to see results?


A. While there are individual differences based on skin condition, changes in skin elasticity and texture are often observed upon completing the initial 3 sessions of the Rejuran cycle. At Kkeut Oriental Medicine Clinic, we monitor skin changes together with you session by session.







Kkeut Oriental Medicine Clinic's Sincerity


Kkeut Oriental Medicine Clinic supports continuous skin regeneration by reducing the cost burden and creating an environment where Rejuran can be received consistently.


Kkeut Oriental Medicine Clinic verifies that dermal layer injection has been properly performed by allowing you to directly confirm the embossing phenomenon in the mirror after the procedure.


Kkeut Oriental Medicine Clinic proceeds by selecting the method most suitable for the patient's condition and goals from manual injection, Potenza pumping tip, or Dermashine.



A Subtle Difference, Different Results — Experience it at Kkeut Oriental Medicine Clinic.