[Collagen Repair] Juvelook Skinbooster

Kkeuthan Clinic Layering Procedure Steps

*1. Pre-Procedure Preparation and Skin Cleansing

- Cooling or numbing cream may be applied as needed.

Kkeuthan Clinic's Skin Booster 4-D Layering Program

*2. Skin Booster 4-Step Layering (using MTS or SecretRF)

Step 1: Skin Booster Ampoule Application

- A thin layer is applied over the entire skin to prepare it for skin booster absorption (priming).

- This induces a skin response in the epidermal layer.

Step 2: Skin Booster Ampoule Application

- After performing shallow needling on the epidermal layer, the ampoule is applied.

Step 3: Skin Booster Ampoule Application

- After needling, targeting the basement membrane at the dermal-epidermal junction, the ampoule is applied.

Step 4: Skin Booster Ampoule Application

- For areas where the patient desires intensive care (e.g., pores, scars), needling is performed, followed by ampoule application to aid localized improvement.

*3. Post-Procedure Soothing Care

- The procedure concludes with soothing the skin using a Jaungo modeling mask.

At our clinic, skin boosters are applied in four layers during a single procedure. This helps the skin booster ingredients to be delivered more broadly and evenly to the skin.

Our clinic's skin booster layering program aims to minimize the risk of bruising, swelling, injection errors, and hypersensitivity reactions that may occur during the procedure.

Kkeuthan Clinic's Skin Booster Absorption Method: Layering Technique

JuveLook ingredients may be difficult to absorb by simply applying them to the skin surface. Therefore, our clinic

utilizes MTS (Microneedle Therapy System) and SecretRF (Needle Radiofrequency) to apply a skin booster layering absorption technique.

JuveLook skin booster particles are approximately 30-50μm in size. While we believe this size can be sufficiently delivered via MTS or SecretRF, we use a layering technique to minimize potential drug loss from conventional application methods and ensure effective delivery of active ingredients.

MTS Layering Technique

MTS creates microscopic channels, approximately 150μm in size, on the skin surface to facilitate the absorption of skin booster ingredients.

At our clinic, we apply a 4-step layering method during MTS procedures to enhance the efficiency of ingredient absorption.

Priming ampoule application to the epidermal layer

Ampoule application to the epidermal layer after shallow needling

Ampoule application to the dermal-epidermal junction

Customized ampoule application to areas requiring intensive care, such as pores and scars

Afterward, the procedure concludes with soothing care, such as a Jaungo modeling mask, which can help reduce the burden of inflammatory reactions.

SecretRF (Needle Radiofrequency) Layering Technique

SecretRF creates microscopic channels, approximately 180μm in size, in the skin and then uses radiofrequency heat to contract these channels. This reduces fluid reflux (overflow) that can occur with conventional needle use, helping JuveLook ingredients to be delivered to the dermal layer with relative precision and minimal loss.

Compared to conventional manual injections, there may be differences in terms of drug loss, but SecretRF offers the advantage of delivering ingredients more uniformly to the desired target layer, the dermis. Additionally, it can reduce pain during the procedure and has the benefit of relatively even absorption.

Similar to MTS procedures, SecretRF also allows for adjustable needle depth, enabling the application of the 4-step layering technique.

At our clinic, we appropriately combine MTS and SecretRF procedures, taking into account each patient's individual skin condition.

Why does our clinic perform procedures in this manner?

JuveLook is originally supplied in powder form.

Therefore, it requires a process of sufficient dilution in saline to stabilize its viscosity.

If direct manual injection is chosen, there is a possibility that the drug may clump and form nodules if dilution is insufficient or injection depth is inappropriate.

Furthermore, if the drug is injected into the subcutaneous fat layer instead of the target dermal layer, it may be difficult to achieve the expected effects.

Even with a consistent dilution process of the drug during injection procedures, it is difficult to completely rule out the possibility of nodule formation. Therefore, we approach procedures in a way that minimizes risks while still achieving beneficial effects.

Our clinic utilizes a layering technique that considers various factors, including drug dilution, viscosity control, creation of injection pathways, and absorption methods. This is tailored to each individual's skin condition to help ensure the effective delivery of the drug.

We believe it is important to approach procedures in a way that maintains the beneficial aspects while reducing risks.

What is Juvelook Skinbooster?

Juvelook is a skinbooster composed of Poly-D,L-lactic acid (PDLLA) and hyaluronic acid (HA) together.

This treatment can help improve skin texture, pores, fine wrinkles, and acne scars. Simultaneously, it is known as a regenerative skinbooster that induces the self-regeneration of collagen and elastin in the dermis, thereby enhancing the overall elasticity and density of the skin.

PDLLA has the characteristic of smaller particles compared to conventional PLLA ingredients (components like Sculptra that have larger particles and can cause nodules). This is advantageous for the skin absorption process of the substance and reflects considerations for safety. Furthermore, it is designed to be delivered deep into the skin while reducing the possibility of inflammation or nodule formation, making it potentially suitable for individuals with sensitive skin.

Juvelook is composed of the following ingredients:

PDLLA 42.5mg (an ingredient that helps stimulate the skin's own collagen production)

Non-crosslinked Hyaluronic Acid 7.5mg (an ingredient that contributes to hydrating the skin and strengthening the skin barrier)

When PDLLA is injected into the dermal layer, it activates fibroblasts, helping them produce collagen and elastin fibers.

Collagen is an important component in forming skin thickness and density, while elastin plays a crucial role in maintaining elasticity.

When these two fibers increase together, it can have a positive impact on improving skin concerns such as fine wrinkles, enlarged pores, and decreased elasticity.

Additionally, PDLLA also stimulates stem cells to induce the differentiation of new fibroblasts.

This can contribute to improving aged cellular structures over time and to regenerating the skin's structure itself.

Fibroblasts, which produce collagen and elastin fibers, are rarely newly generated as we age.

Juvelook Skinbooster helps in the formation of new fibroblasts, replacing those whose function has deteriorated due to aging. Through this, it can aid in long-term collagen and elastin fiber production.

Individuals who may consider the treatment

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• 01. Those concerned about decreased skin elasticity or enlarged pores
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• 02. Those experiencing difficulties with pore issues or acne scars
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• 03. Those wishing for natural skin volume improvement without an artificial look
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• 04. Those concerned about uneven skin texture or fine wrinkles
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• 05. Those who hope for their own collagen production but feel apprehensive about injection treatments
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• 06. Those desiring a natural lifting effect that enhances skin elasticity
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Clinical Background of Juvelook Treatment

Through various studies, it has been reported that PDLLA can have a positive impact on dermal regeneration.

In a study by Kwon et al. (Dermatologic Surgery, 2022), when a PDLLA skinbooster was administered a total of 3 times at 4-week intervals, improvements in skin thickness, dermal density, and elasticity were observed.

Kim et al. (Journal of Cosmetic Dermatology, 2021) observed that PDLLA can also contribute to elastin production. This suggests that a wider range of fiber regeneration can be expected compared to existing collagen-focused products.

In a study by Han et al. (Lasers in Surgery and Medicine, 2020), when treating acne scar patients, it was reported that an MTS (Microneedle Therapy System)-based drug absorption method was useful for drug delivery to the dermal layer, with relatively low epidermal stimulation and side effect rates.

A Message from the Director

Among those who visit us, many experience significant concerns even with just skin texture issues.

This includes cases where pores appear visibly enlarged or skin texture is rough, making makeup feel less smooth.

While such concerns may not be apparent to others, they can be a significant psychological burden for the individual.

For those with these concerns, we recommend considering Juvelook treatment.

This is because the treatment can help soften skin texture, alleviate pore enlargement, and activate the skin's natural regenerative abilities.

If you have experienced fear of pain from injections or concerns about drug loss,

we recommend consulting about Juvelook Skinbooster treatment using our clinic's layering technique.

Treatment Features

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• 01. A complex ingredient of FDA-approved polymeric PLA and hyaluronic acid, which can contribute to improving skin concerns.
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• 02. It induces the skin's own collagen production, allowing for natural changes over time.
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• It can help improve skin elasticity and manage skin texture smoothly. In addition, a positive effect can be expected on improving fine wrinkles or scars caused by acne.
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• The materials used in this treatment are biodegradable and have the characteristic of being absorbed by the body. After a certain period, no residue remains in the body, and they are naturally broken down or absorbed.
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