[Known as IU's Injection] Glutathione White Jade Skin Treatment

Glutathione Brightening Treatment: A Popularly Known Procedure

What is Glutathione?

Glutathione is one of the key antioxidants abundantly distributed in various organs throughout the body. It primarily plays crucial roles in the liver, kidneys, brain, and other organs.

Glutathione can help reduce cell damage by eliminating reactive oxygen species (ROS). Additionally, it aids in the activation of other antioxidant components such as vitamins C and E, thereby positively impacting cell protection and the maintenance of healthy bodily functions.

How Glutathione Contributes to Skin Tone Improvement

Beyond its role in preventing oxidation, glutathione may positively influence skin tone to make it more even and clear.

Inhibition of Tyrosinase Enzyme Activity

Glutathione inhibits the activity of tyrosinase, an enzyme that promotes melanin production. Through this process, it can help prevent the excessive formation of melanin pigments.

Inducing Changes in Melanin Types

Glutathione tends to induce the synthesis of lighter-colored pheomelanin over darker eumelanin. This mechanism helps the overall skin tone appear brighter.

Mitigating Pigment Formation Through Antioxidant Mechanisms

When reactive oxygen species are generated due to UV exposure, heat, or inflammation, melanin production can be accelerated. Glutathione can contribute to reducing the likelihood of pigment formation by eliminating these reactive oxygen species.

Synergistic Action with Vitamin C

Vitamin C helps reduce oxidized glutathione back to its active form, allowing it to be reused. This regenerated glutathione further inhibits melanin synthesis, and the two components work synergistically to achieve positive synergistic effects in skin tone improvement.

Overall, glutathione works by inhibiting melanin production and promoting the synthesis of lighter pigments. These multifaceted mechanisms suggest that skin tone can be improved in a more natural and even way.

Limitations of Common Glutathione Delivery Methods and Our Clinic's Approach

Many people may have encountered glutathione in various forms, such as oral intake or injections. However, these common methods have certain aspects that need consideration.

Considerations for Oral Intake (Oral Glutathione)

Glutathione taken orally has a relatively low absorption rate in the gastrointestinal tract and is largely metabolized in the liver. Therefore, the amount of active ingredient reaching skin tissues may be somewhat limited.

Due to these characteristics, oral intake alone may make it difficult to experience immediate changes in skin tone improvement.

Characteristics and Limitations of Intravenous Injection

When glutathione is administered intravenously, the component disperses throughout the systemic bloodstream. This can make it difficult to deliver the component at a high concentration to specific target areas.

While this can be beneficial for liver function support or systemic antioxidant effects, it's important to consider that its targeting may be somewhat reduced when the goal is to address specific pigmentation or overall skin tone improvement on the face.

Our Clinic's Glutathione Treatment Method

Utilizing Iontophoresis Technique: This method uses electricity to effectively deliver glutathione components close to the dermis layer by penetrating the skin barrier. This approach can compensate for the shortcomings of oral intake or intravenous injections.

Targeted Application to Necessary Areas: Instead of dispersing throughout the body, glutathione can be concentrated and delivered to facial areas requiring pigment reduction or skin tone improvement, promoting absorption.

Use of Highly Concentrated Solution: We prioritize the purity and concentration of glutathione. By using undiluted, highly concentrated ampoules, we help maximize glutathione's inherent potential for antioxidant and skin tone improvement.

Our clinic aims for a glutathione treatment method that is "more direct than oral intake and more targeted than intravenous injections".

Mechanism of Ingredient Absorption in Iontophoresis Treatment

Limitations of Oral Intake: When glutathione is taken orally, its absorption rate in the gastrointestinal tract is inconsistent, and a significant portion is metabolized in the liver. As a result, the active ingredients may not adequately reach skin tissues.

Limitations of Simple Topical Application: The stratum corneum, located on the outer layer of the skin, is a robust protective barrier against external harmful substances. For this reason, water-soluble ingredients like glutathione find it difficult to penetrate deeply into the skin by merely being applied topically.

Core Principles and Benefits of Iontophoresis

Electrical Repulsion: Negatively charged glutathione components are pushed into the skin by electricity of the same polarity. This principle helps effectively deliver the ingredients past the skin's surface barrier.

Electroosmosis: Electrical stimulation induces a microscopic flow of fluid within the skin. This can positively influence the widening of pathways, allowing active ingredients to penetrate deeper into the skin.

Deep Skin Delivery: Iontophoresis ensures that active ingredients do not merely remain on the skin's surface. It can help effectively deliver ingredients like glutathione close to the dermis layer.

In summary, iontophoresis can be considered an efficient approach to absorbing active ingredients "more directly than oral intake, and deeper into the skin than simple topical application".

Recommended Treatment Frequency and Sessions

Recommended Frequency: Once a week

Recommended Sessions: For continuous improvement, it is advisable to receive consistent treatment for at least 5 sessions or more.

Future Maintenance: To maintain the improved skin tone long-term after treatment, periodic supplementary treatments may be beneficial as needed.